False Positive Reaction Due to Methocarbamol in the Screening Test for Vanilmandelic Acid (VMA)

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False Positive Reaction Due to Methocarbamol in the Screening Test for Vanilmandelic Acid (vma).

I N PHEOCHROMOCYTOMA, 3-methoxy-4-hydroxy-rnandelic acid (VMA), a metabolite of epinephrine and norepinephrine, is excreted in urine in abnormally large quantities. Qitlow et al. (1) have developed a semi quantitative screening method for VMA that we have found to be useful and reliable. The procedure is particularly welcome because it permits screening of a large number of urines from hyperten...

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Electrophoretic determination of vanilmandelic acid (VMA) in urine by direct application to cellulose acetate.

‘THE VALUE of vanilmandelic acid (3-methoxy-4-hydroxymandelic acid, 1/MA) in urine for the diagnosis of pheochromocytoma is well recognized. The comprehensive review of VMA analysis by Sunderman (1) reiterates that there is a large difference between normal and pathologic 24-hr. urinary excretion of 1/MA. Such a sharp difference in concentration makes VMA analysis adaptable to a semiquantitativ...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 1964

ISSN: 0009-9147,1530-8561

DOI: 10.1093/clinchem/10.5.447